The “Pirates of the Caribbean” star is not dating the “Scream VI” actress, a source confirmed to Page Six Saturday.
Ortega, 20, also addressed the “ridiculous” claims on her social media account.
“I can’t even laugh,” the “Wednesday” star reportedly wrote on her Instagram Story in a since-deleted post.
“I have never met or worked with Johnny Depp in my life,” she continued. “Please stop spreading lies and leave us alone.”
Rumors began after gossip blog Deuxmoi posted that Depp and Ortega had been spotted together and were possibly working together on “Beetlejuice 2,” which is slated to be released next fall.
The “Edward Scissorhands” star most recently made headlines for his romance with Joelle Rich, a London-based attorney who represented the actor in his libel case against the Sun in 2020.
An insider told US Weekly last year that Rich was married when she and Depp first started dating but was in the middle of divorcing her husband.
The Oscar nominee and the high-profile lawyer split in October 2022.
Prior to that, Depp was married to Amber Heard from 2015 to 2017.
Last year, he won a defamation case against the “Aquaman” star, claiming the 37-year-old lied about him abusing her.
Heard was ordered to pay her ex-husband $10 million in compensatory damages and $350,000 in punitive damages.
Johnny Depp, 60, is not dating 20-year-old Jenna Ortega. Johnny Depp, 60, is not dating 20-year-old Jenna Ortega