50 Cent is reigniting his old feud with Madonna by taking aim at her bum this time.
“who the f—k did this?” the “Many Men” rapper wrote via Instagram Friday alongside a photo of Madonna next to a cartoon ant.
Referencing the “Like A Virgin” singer’s behind, 50 Cent continued, “She’s rich how the hell she didn’t get it fixed I want the f—king doctors name right now. I mean damn it man ! LOL.”
The “In da Club” rapper also included a video of the pop legend, 65, performing at the 02 Arena in London earlier this month that zooms in to show her behind.
Madonna’s fans rushed to the comments section to defend the Grammy-winning artist, including one person who told the rapper that his Instagram roasting was “not even funny.”
“It’s very sad when a man attacks a woman and criticizes her body. Shame on you,” a second added.
“Me wondering who asked? Stop bullying THE QUEEN OF POP,” another wrote.
50 Cent — whose real name is Curtis James Jackson III — has a reputation for making digs at the “Hung Up” songstress.